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Management of chronic agony continues to characterize a place of excellent unmet biomedical will need. Whilst opioid analgesics are usually embraced since the mainstay of pharmaceutical interventions in this location, they suffer from sizeable liabilities which include habit and tolerance, and also despair of respiration, nausea and Continual const

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Pinpointing the mechanism of motion (MOA) of novel or In a natural way occurring compounds mainly depends on assays personalized for specific focus on proteins. Here we explore an alternate approach determined by sample matching response profiles received applying cultured neuronal networks. Conolidine and cannabidiol are plant-derivatives with ide

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